Indeed, PP2A has been shown to regulate, for example, RAF-MEK-ERK and PI3K-AKT pathways (Sablina et al, 2010; Kauko & Westermarck, 2018; Fowle et al, 2019), but whether there are processes beyond kinase signaling that are relevant to RAS/PP2A co-operation in cancer is poorly understood. Here, PTPA is linked to cancer.