NFE2L2 and neoplasm: On the otherhand, the synergic administration of 9 with docetaxel(16) has shown apoptosis induction and G2/M phase arrestagainst prostatic cancer cells.25 In anotherstudy, 9 was shown to significantly enhance the abilityof rapamycin (17) to induce colon cancer cell apoptosisand inhibit tumor growth in xenograft nude mice through the autophagy/p62/Nuclearfactor erythroid 2-related factor 2 (Nrf2) pathway.26Figure 5 shows different combination treatments with garlic-derived compounds.