One example is the formationof liposomes loaded with 5 and decorated on their surfacewith the RAGE antibody, which is overexpressed in triple-negativebreast cancer cells, targeting them.61 Also, 49 (Figure 12) has been encapsulated in DOTA-PLGA nanoparticles decorated on theirsurface with HA for the treatment of colon cancer. This evidence concerns the gene AGER and cancer.