CD274 and neoplasm: Furthermore, high expression of CD63 and PD-L1 was associated with more aggressive tumours, as represented by lymph node involvement (p<0.0001 for both, Table S3), modified Dukes’ criteria grade (both, p<0.0001, Table S3), and an increased probability to die within 60 months (both, p<0.0001 Fig. 9D, E, J, K).