Infection with a Cre-GFP retrovirus (RV) during proliferation led to a clear reduction in MPC1 protein in the Mpc1 fl/fl NSPCs (hereafter called MPC1 cKO) compared to virus-treated Mpc1 WT NSPCs (MPC1 WT), as shown by immunohistochemistry (fig. The gene discussed is MPC1; the disease is infection.