By independent-sample t test, CD247 (-0.805 [-1.323 - -0.288]; t = -4.323, p = 0.012), IL-2Rβ (-0.514 [-0.862 - -0.166]; t = -4.102, p = 0.015) and TGF-βR3 (-0.835 [-1.288 - -0.382]; t = -5.120, p = 0.007) were significantly down-regulated in sepsis cells versus normal cells, while IL-1R2 (4.028 [2.904–5.153]; t = 9.950, p = 0.001) was reversely up-regulated. The gene discussed is TGFBR3; the disease is Sepsis.