We speculated the involvement of lncRNAs (LOC105376878, LINC00944, LOC727751) and miRNAs (hsa-miR-330-5p, hsa-miR-199b-5p, hsa-miR-3909) in the TGF-βR3 associated ceRNA regulatory network, which could augment the TGF-βR3 expression and in turn prolong the survival in patients of sepsis. Here, TGFBR3 is linked to Sepsis.