Further, LF and NT5DC3 protein combination significantly inhibited the development of HT29 tumors (comparing with the untreated groups, P < 0.05), underscoring the tumor suppressor NT5DC3 corroborates with LF to anti-tumor roles mainly through the activation of the NT5DC3 level in diabetic mouse models (Fig. 2C, E). The gene discussed is NT5DC3; the disease is neoplasm.