METTL3-mediated m6A modification leads to increased nuclear accumulation of LncRP11, and then, LncRP11 reduces the Siah1 and Fbxo45 levels and increases Zeb1 stability by forming the RP11-hnRNP A2B1-mRNA complex, ultimately playing an oncogenic role in colorectal cancer (CRC)43. Here, METTL3 is linked to colorectal carcinoma.