For instance, we found that the SNP (rs74181299) with the highest PPA for atrial fibrillation and the cardiac muscle-eQTL for CEP68 (PPA ≈ 1, Fig. 6g–i), is in moderate LD (R2 = 0.75) with the previously identified index variant rs2723064 (PPA ≈ 0, 4.2 kb upstream)2,67. Here, CEP68 is linked to atrial fibrillation.