CSN1S1 and myopathy: Mutations in CASA complex components have been associated with different neuromuscular conditions: BAG3 mutations are associated with myopathies, neuropathies, and also cardiomyopathies [21–28]; STUB1 mutations are linked to spinocerebellar ataxias [29–32]; HSPB8 mutations cause distal hereditary motor neuropathy type II (dHMNII), Charcot-Marie-Tooth type 2 L (CMT2L) disease, and myopathies [33–36].