ANGPTL7 and neoplasm: Because Angptl7 expression is low in whole tumor lysates, knockdown was confirmed on a protein level by ELISA of tumor interior, and Angptl7 protein expression was significantly reduced in KD1 and KD3 in the tumor interior, where Angptl7 expression is higher than in whole tumor lysates (Fig. 3C and SI Appendix, Fig S6A).