Among 160 participants for whom both glomerular WWC1 expression levels (determined by RNA sequencing) and renal survival data were available, 35 patients (21%) reached the composite outcome of either end-stage renal disease (ESRD) or at least 40% baseline estimated glomerular filtration rate (eGFR) decline at an average of 520 days. This evidence concerns the gene WWC1 and chronic kidney disease.