Compared with intratumoral IH, peritumoral IH had higher frequencies of interactions between CD20+CXCR5+ and CD4+FOXP3+, CD4+FOXP3−, but not CD8+ cells (univariate logistic regression P < 0.05; Fig. 5C). The gene discussed is CXCR5; the disease is isolated hemihyperplasia.