TPM1 and familial dilated cardiomyopathy: In humans, DCM‐causing mutations were also identified in a large number of genes including those encoding cytoskeletal proteins such as FLNC, nuclear membrane protein LMNA or involved in sarcomere stability (Titin, TNNT2, MYH7, TPM1) but also RNA‐binding protein RBM20 (McNally & Mestroni, 2017).