While lncRNAs directly regulated by p53 include multiple lncRNAs with an established tumor suppressive role (Table 1), lncRNAs recurrently down‐regulated by p53 via p21 also include host genes of small nucleolar RNA families (snoRNAs), such as SNHG1, SNHG10, SNHG12, and SNHG17 (Fig. 3D). This evidence concerns the gene SNHG1 and neoplasm.