It is a broad-spectrum tumour marker and its level increases dramatically after the development of many tumours [13].CA211 is mainly found in the cytoplasm of tumour cells and can be released into the blood when tumour cells are necrotic or lysed, which is useful for the diagnosis and treatment of squamous carcinoma [14].NSE is an acidic protease that is found in neural tissue and the neuroendocrine system and mainly acts in the glycolytic pathway [15]. This evidence concerns the gene ENO2 and neoplasm.