Therefore, it has been hypothesized that SOCS7 downregulation by hsa-miR-4299, which results in STAT3 activation and promotes inflammation through the IL-6/STAT3 axis, might be a mechanism that results in persistent viral RNA in the fibroblasts, leading to chronic CHIKV disease [47], although further experimentation is necessary to confirm this. Here, IL6 is linked to glycogen storage disease VI.