Chemokines commonly found activated in HFRS and NE attract mononuclear cells (CCL2 and CCL5) with a preference for Th1 lymphocytes, natural killer (NK) cells, and CD8+ lymphocytes (CXCL9 and CXCL10) [144,145,146]. The gene discussed is CD8A; the disease is hemorrhagic fever with renal syndrome.