HLA-DQA1 and hepatocellular carcinoma: One study [79] compared an HCV-related HCC group with an anti-HCV seronegative control group and identified two genome-wide significant variants, namely rs2596542 in the MICA (MHC class I polypeptide-related sequence A) gene and rs9275572 in the HLA-DQA and HLA-DQB loci.