The IHC staining of co-cultures with GFP/luc-HT-29 revealed an effective tumor cell lysis and almost no remaining tumor cells in GLV-0b347-infected co-cultures compared to MOCK-treated co-cultures, as indicated by staining with hematoxylin and eosin (H&E) (Figure 5D) and EpCAM antibody (Figure 5E). This evidence concerns the gene EPCAM and neoplasm.