PPP3CC and HIV-1 infection: Intriguingly, genes present in these four KEGG BRITE classifications were restricted to HIV-1-infected individuals receiving ART and specific to different periods of treatment (Figure 3b–e), except the genes rapgfe2 and ppp3cc. The gene rapgfe2 was observed throughout the whole period of HIV-1 infections (Figure 3e), and ppp3cc appeared after patients received ART (Figure 3c–e).