CD276, CD44, and VTCN1 were significantly upregulated in IS6 tumours in the TCGA cohort, whereas BTNL2, CD244, CD276, ICOSLG, TMIGD2, TNFRSF18, KIR3DL1, PDCD1, TNFRSF4, TNFRSF8, TNFSF14, TNFSF18, and VTCN1 were overexpressed in IS6 tumours in the GEO cohort. Here, TMIGD2 is linked to neoplasm.