Carriers of the homozygote TT genotype of the R262W polymorphism within the Src homology 2B (SH2B) protein 3 (LNK/SH2B3) gene show augmented platelet–neutrophil aggregation leading to heightened atherosclerosis and atherothrombosis in an oxidized phospholipid (oxPL)-dependent manner [31]. This evidence concerns the gene SH2B3 and atherosclerosis.