To understand whether the NLRP3 inflammasome promotes NET formation during atherosclerosis, mice deficient with Abca1/g1 in myeloid cells were engineered with Nlrp3/caspase1/caspase11 deletion and bone marrow cells of these mice were transported to Ldlr-/- mice, which were fed with Western-type diet (WTD) [68]. Here, NLRP3 is linked to atherosclerosis.