Moreover KEGG pathway enrichment analysis indicated that cancer related pathways such as protein digestion and absorption, platelet activation [65], focal adhesion, Amoebiasis [66], human papillomavirus infection [69], AGE-RAGE signaling pathway in diabetic complications [70], and relaxin signaling pathway [71] were significantly enriched which was in agreement with the results of other studies. Here, RENBP is linked to amebiasis.