DEPDC1 was reported to be overexpressed at both mRNA and protein levels in nasopharyngeal carcinoma tissues compared with normal or non-tumor tissues, and the siRNA-mediated deletion of DEPDC1 significantly inhibited the proliferation of nasopharyngeal carcinoma cell lines CNE-1 and HNE-1 [27]. The gene discussed is DEPDC1; the disease is nasopharyngeal carcinoma.