The representative pathways activated in the high-risk group included “IL-17 signaling pathway”, “Pentose phosphate pathway”, “Pentose and glucuronate interconversions”, “Viral protein interaction with cytokine and cytokine receptor”, “NOD-like receptor signaling pathway” and “Transcriptional misregulation in cancer”, while the pathways suppressed in the high-risk group included “Aldosterone synthesis and secretion”, “Alanine, aspartate and glutamate metabolism”, “Vascular smooth muscle contraction” and “Glycosaminoglycan biosynthesis - heparan sulfate/ heparin” (Fig. 5A). This evidence concerns the gene IL17A and cancer.