For the Bai et al.34 data (Kymriah in ALL), we compared accuracy of classifying CR versus NR/RL groups using the 28-gene signature panel to a bivariate classifier trained using the early memory (CD8+CD45RO−CD27+) and exhausted (CD8+PD1+) immunophenotype frequencies calculated from CITE-seq antibody tags (Supplementary Fig. 13d). The gene discussed is CD8A; the disease is acute lymphoblastic leukemia.