SMARCD3 and neoplasm: To determine the functions of SMARCD3 in the genome architecture that regulates the gene expression of components involved in cell migration and tumour metastasis, we performed assay for transposase-accessible chromatin using sequencing (ATAC-seq) to obtain nucleosome-free fragments (<100 base pairs) and mononucleosome fragments (180–247 base pairs)34.