Fusion genes, such as SS18-SSX, EWSR1-FLI1 and PAX3-FOXO1, are responsible for the generation of synovial sarcoma (SS), Ewing’s sarcoma (ES) and alveolar rhabdomyosarcoma (ARMS), respectively [5–10]. Here, FOXO1 is linked to alveolar rhabdomyosarcoma.