KDR and neoplasm: For antiangiogenic therapy, iodinated VEGF is the most studied radiolabeled VEGF tracer.212–215 VEGF, VEGFR, and related integrins can also be labeled with 18F,216,21799mTc,218–220111In,220,22164Cu,218,222,223 and 89Zr,224 but most of these are simply for imaging of the tumor vasculature and can help to visualize tumors and metastatic lesions usually overexpressing VEGFR or VEGF.