ATXN1 and neurodegenerative disease: In this section we provide an example of the inferences that can be easily made using the EvoPPI3 version here reported, namely the identification of novel therapeutic targets for spinocerebellar ataxia type 1 (SCA1) neurodegenerative disease, that is caused by the expansion of the polyglutamine repeat of Ataxin-1 protein that is encoded by the ATXN1 gene (GeneID 6310).