Among the putative risk variants examined in the present study were two missense variants (SLC3A1 p.I192V and p.S698G) previously implicated in a recessive form of cystinuria affecting English and potentially also French Bulldogs and a missense variant SLC7A9 p.A217T discovered in the heterozygous state in one English Bulldog case (OMIA 000256–9615) [23, 24]. This evidence concerns the gene SLC3A1 and cystinuria.