To restrict our space we considered interactions in the following categories: (1) Interactions of the developmentally important VSX2 locus internally and with all other common genetic variants; (2) Interactions between the Retinoid cycle loci; (3) Interactions of the Oguchi syndrome loci; (4) Interaction of all loci with genetically defined sex; and (5) Interactions between rare burden levels in genes and nearby common SNPs. Here, VSX2 is linked to Oguchi disease.