NRXN1 and autism: To systematically characterize the contribution of gene dosage and genomic position of CNV deletions in NRXN1 to autism-relevant behavioral phenotypes in both males and females, we performed a battery of behavioral tests (S1 Fig) in adult mice (≥ 3 months of age) from these three mouse models with WT, heterozygous, and homozygous deletions of specific parts of Nrxn1.