CREB1 and esophageal squamous cell carcinoma: In the present study, we found the regulatory effect of miR-942-5p on targeting CST1 and revealed the fact that the miR-942-5p/CST1 axis affects the migration and invasion of ESCC cells by regulating the downstream MEK/ERK/CREB pathway, which might provide a new promising target for diagnosis and treatment of ESCC.