RAG1 and clostridium difficile infection: Rag1-/- (B- and T-lymphocytes deficient) and Rag-γc-/- mice (ILC and B- and T-lymphocytes deficient) were assessed using a similar infection model, and Rag-γc-/- mice developed more severe CDI compared to the WT and Rag1-/- mice [266].