EIF5A and cancer: Moreover, elevated eIF5A2 expression carries unfavorable prognostic implications for several cancer and both eIF5A1 and eIF5A2 have been advanced as cancer biomarkers (Bai et al., 2018; Caraglia et al., 2013; Clement et al., 2006; Liu et al., 2016; Mathews and Hershey, 2015; Nakanishi and Cleveland, 2016; Pallmann et al., 2015; Wang et al., 2013), thus further expanding the potential use for our new mouse models.