They found that a comparison of TB2 and TB1 responses (QFT-Plus TB2 less TB1, which was positively correlated with CD8 T-cell response—r = 0.731, p < 0.001) was higher in active TB cases, while the HBHA-induced IFN-γ response was significantly higher in the LTBI (median 69.67 pg/ml; both p < 0.0001). This evidence concerns the gene CD8A and tuberculosis.