In particular, TB1 and TB2 responses were similar in each group and did not present statistically significant differences (p > 0.05), although TB1 IFN-γ levels were slightly higher in active TB (4.03 IU/ml vs 3.14 IU/ml p > 0.05) and TB2 IFN-γ levels were slightly higher in LTBI (2.76 IU/ml vs 1.44 IU/ml, p > 0.05). This evidence concerns the gene REEP5 and tuberculosis.