AFP and fungal infectious disease: Due to the rapid increase inthe number of fungal infections, antifungal proteins are of particularinterest.1 The Aspergillus giganteus antifungal protein (AFP), a cysteine-rich antifungal protein fromcertain Ascomycetes, was first isolated and characterized in 1965.2 AFP is a promising biotechnological antifungalcompound used to fight against filamentous fungi.3 Until today, several members of this protein group weredescribed from taxonomically distinct species, such as Aspergillus spp., Fusarium spp.