As shown in Fig. 4D, the results showed that these DEGs were enriched in the GO biological terms performing functions in biological processes related to lipoprotein metabolic processes, regulation of interleukin-6 production, and the innate immune response, implying that Amuc_1100 may alleviate disorders of lipid metabolism and inflammatory responses associated with obesity. The gene discussed is IL6; the disease is obesity due to melanocortin 4 receptor deficiency.