Autosomal recessive mutations lead to early‐onset atypical parkinsonism with uncharacterized neuropathology or epileptic encephalopathy with neuronal tau pathology indicating loss of SYNJ1 function is associated with Tau neuronal pathology and development of atypical parkinsonism (Hardies et al., 2016; Schneider & Alcalay, 2017). This evidence concerns the gene MAPT and Epileptic encephalopathy.