Here, we migrated this assay to the Luminex magnetic bead platform, and utilized a panel of eight previously identified blood-borne IgG aAB biomarkers comprising four prodromal AD (MCI) biomarkers (cDNA clone MGC:31944 IMAGE: 4878869, HSH2D, GCDH, CCL19), three mild-moderate AD biomarkers (LGALS1, ICAM4, DNAJC8) from our earlier studies (Table 2), as well as an anti-IgG Kappa light chain antibody to measure individual IgG levels [38, 40]. Here, ICAM4 is linked to Alzheimer disease.