TNF and familial Mediterranean fever: The subclinical inflammation may persist in the period between attacks, and increased release of proinflammatory cytokines (including interleukin-6, interleukin-8, and tumor necrosis factor-α [TNF-α]), selectins (P, E, and L-selectins), and peptides (e.g., serotonin and thrombomodulin) may play a role in FMF’s inflammatory phases [2].