In addition, deeper and more research indicated that tumor-infiltrating dendritic cells (DC) are inclined to promote immunosuppression and tolerance in TME, rather than drive anticancer immunity [32]; Our results showed that the expression of the MYL5 gene was negatively relevant to DC infiltration in breast cancer, and this could suggest that MYL5 gene could affect the prognosis by regulating DC infiltration level. Here, MYL5 is linked to breast carcinoma.