Previous research has shown that the reduction of peripheral blood EETs is not only closely associated with the deterioration of neurological function after ischemic stroke but also with the degree of carotid artery stenosis and plaque instability in patients with cerebral infarction and is regulated by the gene encoding sEH (epoxide hydrolase 2, EPHX2) (7–9). Here, EPHX2 is linked to brain infarction.