INS and diabetes mellitus: Morphine and oxycodone, many antimicrobials like quinolones, sulfamethoxazole with trimethoprim, glycopeptides, and aminoglycosides, alongside certain anticoagulants such as warfarin, heparin, dabigatran, and rivaroxaban, for dialysis-dependent patients with diabetes insulin and insulin secretagogues all require a dose adjustment and reduction for dialysis-dependent patients70.