After tuberculosis is swallowed, the macrophage can (1) release hydrolytic enzymes to kill tuberculosis; (2) produce interleukins, such as interleukin-1, interleukin-6, interleukin-10, tumour necrosis factor alpha, and interferon gamma; (3) uptake, process, and present effective antigens to T lymphocytes and sensitize T cells to eliminate tuberculosis; and (4) trigger programmed death of themselves, such as apoptosis, autophagy, and necroptosis, to kill tuberculosis [4]. This evidence concerns the gene IFNG and tuberculosis.