Similarly, MIF and PRDX6 were significantly upregulated in MM cell lines compared to normal bone marrow stromal cell lines HS5.And the expression levels of AKR1C3, CDKN2A, CP and TF in MM cell lines were statistically lower than these in HS5 cell line (Supplementary Figures 8A-F). Here, CDKN2A is linked to Miyoshi myopathy.