Among them,STAT3 and MYC were significantly correlated with all prognostic genes, in which positively correlated with FLRT2, ODC1, SEL1L3 and VDR, and negatively correlated with ATP6V0E2 (Figure 4).These results indicates that the prognostic genes we screened are important downstream molecules of classic cancer driver genes like STAT3 and MYC. This evidence concerns the gene ATP6V0E2 and cancer.