However, ING3 expression was not associated with overall survival (HR=0.77, 95% CI: 0.41-1.12), tumor size (OR=0.67, 95% CI: 0.33-1.37), tumor differentiation (OR=0.86, 95% CI: 0.36-2.09) and gender (OR=1.14, 95% CI: 0.78-1.66).<h4>Conclusion</h4>This study showed that the expression of ING3 was associated with better prognosis, suggesting that ING3 may be a potential biomarker for cancer prognosis.<h4>Systematic review registration</h4>https://www.crd.york.ac.uk/prospero/, identifier (CRD42022306354). This evidence concerns the gene ING3 and cancer.