Similarly, low MCPH1/BRIT1 expression in oesophageal squamous cell carcinoma, renal clear cell carcinoma and testicular germ cell tumours predicted reduced RFS while high MCPH1/BRIT1 expressions in oesophageal adenocarcinoma, renal papillary cell carcinoma, pancreatic ductal adenocarcinoma and stomach adenocarcinoma predicted reduced RFS (71). The gene discussed is MCPH1; the disease is esophageal adenocarcinoma.